Drug Targets

Conferences & Courses
Targeting Key Antibacterial R&D Challenges Targeting Key Antibacterial R&D Challenges
October 27-28, 2014 | Boston, MA

Screening and Functional Analysis of 3D Models Screening and Functional Analysis of 3D Models
November 18-19, 2014 | Boston, MA
CHI' s Screening and Functional Analysis of 3-D Models conference, November 18-19, 2014, Boston, MA, will explore the use of 3D models to profile compound action and predict toxicity and efficacy.

Phenotypic Drug Discovery Part 2 Phenotypic Drug Discovery Part 2
November 18-19, 2014 | Boston, MA
Cambridge Healthtech Institute’s Phenotypic Drug Discovery Conference, November 17-18, 2014, Boston, MA, will address the advantages of phenotypic screening vs.




Life Science Media Library
Introduction to Adoptive T Cell Therapies DVD Introduction to Adoptive T Cell Therapies DVD
May 5, 2014 |
This digital course will aim to guide the researcher in designing studies for accelerated stability testing of biologics. The course will begin with basic underlying concepts governing protein drug product stability, and focus on design principles for meaning stress and accelerated stability testing of not only the protein of interest but also of excipients and primary packaging components. Strategies to handle complexities arising from their interactions will also be discussed.
Allosteric Modulators of GPCRs Allosteric Modulators of GPCRs
September 23, 2013 |
Allosteric modulators represent a novel paradigm to therapeutically target G-protein-coupled receptors (GPCRs). However, identification and characterization of allosteric modulators using standard functional assays remain elusive due to the ‘context-dependent phenomena’. This course will discuss important aspects of hit identification and validation of allosteric modulators in GPCR research activity.
First Principles in Binding Kinetics First Principles in Binding Kinetics
June 6, 2012 |
This course will address the questions on “why should I care about kinetics?” and “how can I understand and predict Structure-Kinetics relationships?” We will first review the role of binding kinetics in drug action and then focus on the particular case of protein-ligand non-covalent complexes, reviewing what is known so far about the structural determinants of binding kinetics. This course will help you with a better understanding and increased awareness of current state of the chemistry and pharmacology of binding kinetics.




Publications, Reports, & Whitepapers
Biomarkers: Neurobiomarkers and Neurodiagnostics
Biomarkers: Discovery and Development for a Diagnostic Approach to Neurodegenerative Disorders, published by Insight Pharma Reports has a focus in biomarkers for neurodegenerative diseases and diagnostic applications in development.
MicroRNA: An Insight to miRNA-based microarrays, diagnostics and therapeutics
This report analyzes recent trends in medicinal chemistry and evaluates their significance for advancing R&D productivity. We consider technological modalities and market dynamics, with an emphasis on outsourcing and user views on the implications of current practices.