Drug Targets

Conferences & Courses
Targeting Mitochondrial Dysfunction & Toxicity Targeting Mitochondrial Dysfunction & Toxicity
March 19-20, 2015 | Cambridge, MA
Targeting Mitochondrial Dysfunction & Toxicity Conference March 18-19, 2015 | Boston, MA Mitochondrial failure and/or dysfunction has been identified as an important factor in diseases ranging from neurodegenerative conditions (ALS, Alzheimer’s, Parki

Protein & Antibody Engineering Protein & Antibody Engineering
March 31 - April 1, 2015 | Shanghai China
The field of protein engineering is at an exciting point in its development, with new generations of protein and antibody formats entering the market, improved understanding of structure-function relationships, and creative engineering that promises to op

Phage & Yeast Display Phage & Yeast Display
March 31 - April 1, 2015 | Shanghai China
Antibody generation, targeting membrane proteins, screening against challenging targets, generating novel constructs such as ADCs and bispecifics are all examples of today’s vast and important applications of screening and display technologies.




Life Science Media Library
Introduction to Adoptive T Cell Therapies DVD Introduction to Adoptive T Cell Therapies DVD
May 5, 2014 |
Adoptive T cell therapy has the potential to increase antitumor immunity, enhance vaccine efficacy, and limit graft-versus-host disease (GVHD). Recent advances in protein engineering and molecular biology have increased the feasibility of using genetically engineered T cells to treat disease, leading to an influx of new discoveries and techniques. This course DVD will educate viewers on the basic rules of adoptive T cell therapies before delving into strategies for developing chimeric antigen receptors (CARs) and T cell receptors (TCRs).
Allosteric Modulators of GPCRs Allosteric Modulators of GPCRs
September 23, 2013 |
Allosteric modulators represent a novel paradigm to therapeutically target G-protein-coupled receptors (GPCRs). However, identification and characterization of allosteric modulators using standard functional assays remain elusive due to the ‘context-dependent phenomena’. This course will discuss important aspects of hit identification and validation of allosteric modulators in GPCR research activity.
First Principles in Binding Kinetics First Principles in Binding Kinetics
June 6, 2012 |
This course will address the questions on “why should I care about kinetics?” and “how can I understand and predict Structure-Kinetics relationships?” We will first review the role of binding kinetics in drug action and then focus on the particular case of protein-ligand non-covalent complexes, reviewing what is known so far about the structural determinants of binding kinetics. This course will help you with a better understanding and increased awareness of current state of the chemistry and pharmacology of binding kinetics.




Publications, Reports, & Whitepapers
Biomarkers: Neurobiomarkers and Neurodiagnostics
Biomarkers: Discovery and Development for a Diagnostic Approach to Neurodegenerative Disorders, published by Insight Pharma Reports has a focus in biomarkers for neurodegenerative diseases and diagnostic applications in development.
MicroRNA: An Insight to miRNA-based microarrays, diagnostics and therapeutics
This report analyzes recent trends in medicinal chemistry and evaluates their significance for advancing R&D productivity. We consider technological modalities and market dynamics, with an emphasis on outsourcing and user views on the implications of current practices.