Drug Targets

Conferences & Courses
Anti-Inflammatories: Small Molecule Approaches Anti-Inflammatories: Small Molecule Approaches
April 23-24, 2014 | San Diego, CA
JAK kinase inhibitors will probably be the first new class of oral anti-inflammatories on the market, with the first one likely to receive approval end of 2012.

Drug Discovery Chemistry Drug Discovery Chemistry
April 23-25, 2014 | San Diego, CA

Protein-Protein Interactions Protein-Protein Interactions
April 23-24, 2014 | San Diego, CA
Cambridge Healthtech Institute' s conference on Protein-Protein Interactions has established itself as a successful and well attended event year after year.




Life Science Media Library
Allosteric Modulators of GPCRs Allosteric Modulators of GPCRs
September 23, 2013 |
The advancing technology of high-throughput screening is changing the type of molecules found. With protein function more physiologically relevant, the quality of the molecules that pharmacologists and medicinal chemists must deal with is changing. This course will familiarize researchers with the tools needed to exploit this potentially fruitful area of new drug discovery through discussion of allosteric molecules, detection of allosterism, and quantifying allosterism for chemical lead optimization.
Pharmacology and Drug Discovery in the Allosteric World Pharmacology and Drug Discovery in the Allosteric World
November 3, 2011 |
The advancing technology of high-throughput screening is changing the type of molecules found. With protein function more physiologically relevant, the quality of the molecules that pharmacologists and medicinal chemists must deal with is changing. This course will familiarize researchers with the tools needed to exploit this potentially fruitful area of new drug discovery through discussion of allosteric molecules, detection of allosterism, and quantifying allosterism for chemical lead optimization.
Targeting Cancer Stem Cells Targeting Cancer Stem Cells
November 3, 2011 |
Cancer stem cells (CSCs) have been identified in several types of cancer, and may play a role in tumorigenic growth, metastasis, and therapeutic resistance. New anticancer therapeutics are being developed that will inhibit tumor growth and reduce tumor-initiating cell frequency, improving clinical cancer therapy. The development of new agents that block key CSC pathways will be described, as well as a novel assay for tracking CSCs in cell populations without the need to isolate them, and a CSC screening strategy for discovering therapeutic antibodies.




Publications, Reports, & Whitepapers
MicroRNA: An Insight to miRNA-based microarrays, diagnostics and therapeutics
This report analyzes recent trends in medicinal chemistry and evaluates their significance for advancing R&D productivity. We consider technological modalities and market dynamics, with an emphasis on outsourcing and user views on the implications of current practices.
Epigenetics: Emerging Targets, Available Technologies, Expert Interviews, and an Epigenetic Community Perspective
Epigenetics: Emerging Targets, Available Technologies, Expert Interviews, and an Epigenetic Community Perspective provides an overview of the scientific and technological landscape from which both the diagnostic and therapeutic sectors of the nascent epigenetics industry are emerging, plus a qualitative analysis of the scientific, technological, and commercial achievements and challenges facing both sectors.