Drug Targets

Conferences & Courses
PEGS: the essential protein engineering summit	PEGS: the essential protein engineering summit
May 4-8, 2015 | Boston, MA
PEGS - The Essential Protein Engineering Summit is the premier event for antibody and protein science research and the biologics industry, with more than 1,800 participants in attendance from over 30 countries.

Biomarkers & Diagnostics World Congress Biomarkers & Diagnostics World Congress
May 5-7, 2015 | Philadelphia, PA
The signature event/conference in Cambridge Healthtech Institute' s Biomarker Series, The Biomarker World Congress/conference 2013 is dedicated to all areas of biomarker research spanning the pharmaceutical and diagnostic pipeline.

Mastering Medicinal Chemistry Mastering Medicinal Chemistry
June 10-11, 2015 | Boston, MA
Cambridge Healthtech Institute’s Twelfth Annual Mastering Medicinal Chemistry will showcase informative, high quality case studies and successful strategies to tackle the problems facing the medicinal chemistry landscape.

Life Science Media Library
Introduction to Adoptive T Cell Therapies DVD Introduction to Adoptive T Cell Therapies DVD
May 5, 2014 |
Adoptive T cell therapy has the potential to increase antitumor immunity, enhance vaccine efficacy, and limit graft-versus-host disease (GVHD). Recent advances in protein engineering and molecular biology have increased the feasibility of using genetically engineered T cells to treat disease, leading to an influx of new discoveries and techniques. This course DVD will educate viewers on the basic rules of adoptive T cell therapies before delving into strategies for developing chimeric antigen receptors (CARs) and T cell receptors (TCRs).
Allosteric Modulators of GPCRs Allosteric Modulators of GPCRs
September 23, 2013 |
Allosteric modulators represent a novel paradigm to therapeutically target G-protein-coupled receptors (GPCRs). However, identification and characterization of allosteric modulators using standard functional assays remain elusive due to the ‘context-dependent phenomena’. This course will discuss important aspects of hit identification and validation of allosteric modulators in GPCR research activity.
First Principles in Binding Kinetics First Principles in Binding Kinetics
June 6, 2012 |
This course will address the questions on “why should I care about kinetics?” and “how can I understand and predict Structure-Kinetics relationships?” We will first review the role of binding kinetics in drug action and then focus on the particular case of protein-ligand non-covalent complexes, reviewing what is known so far about the structural determinants of binding kinetics. This course will help you with a better understanding and increased awareness of current state of the chemistry and pharmacology of binding kinetics.

Publications, Reports, & Whitepapers
Biomarkers: Neurobiomarkers and Neurodiagnostics
Biomarkers: Discovery and Development for a Diagnostic Approach to Neurodegenerative Disorders, published by Insight Pharma Reports has a focus in biomarkers for neurodegenerative diseases and diagnostic applications in development.
MicroRNA: An Insight to miRNA-based microarrays, diagnostics and therapeutics
This report analyzes recent trends in medicinal chemistry and evaluates their significance for advancing R&D productivity. We consider technological modalities and market dynamics, with an emphasis on outsourcing and user views on the implications of current practices.