Drug Targets

Conferences & Courses
Cancer Targets for Antibody Therapeutics Cancer Targets for Antibody Therapeutics
January 19-20, 2015 | San Diego, CA
Cancer Targets for Antibody Therapeutics explores new directions in the discovery of emerging and challenging targets in this space – and the steps that will be required in developing these into next generation therapeutics.

Phenotypic Screening Phenotypic Screening
January 26-27, 2015 | San Diego, CA
CHI' s Twelfth Annual High-Content Analysis meeting, January 26-27, 2015 the premier event showcasing the latest advancements in HCA applications and technologies.

Targeting Mitochondrial Dysfunction & Toxicity Targeting Mitochondrial Dysfunction & Toxicity
March 19-20, 2015 | Cambridge, MA
Targeting Mitochondrial Dysfunction & Toxicity Conference March 18-19, 2015 | Boston, MA Mitochondrial failure and/or dysfunction has been identified as an important factor in diseases ranging from neurodegenerative conditions (ALS, Alzheimer’s, Parki

Life Science Media Library
Introduction to Adoptive T Cell Therapies DVD Introduction to Adoptive T Cell Therapies DVD
May 5, 2014 |
Adoptive T cell therapy has the potential to increase antitumor immunity, enhance vaccine efficacy, and limit graft-versus-host disease (GVHD). Recent advances in protein engineering and molecular biology have increased the feasibility of using genetically engineered T cells to treat disease, leading to an influx of new discoveries and techniques. This course DVD will educate viewers on the basic rules of adoptive T cell therapies before delving into strategies for developing chimeric antigen receptors (CARs) and T cell receptors (TCRs).
Allosteric Modulators of GPCRs Allosteric Modulators of GPCRs
September 23, 2013 |
Allosteric modulators represent a novel paradigm to therapeutically target G-protein-coupled receptors (GPCRs). However, identification and characterization of allosteric modulators using standard functional assays remain elusive due to the ‘context-dependent phenomena’. This course will discuss important aspects of hit identification and validation of allosteric modulators in GPCR research activity.
First Principles in Binding Kinetics First Principles in Binding Kinetics
June 6, 2012 |
This course will address the questions on “why should I care about kinetics?” and “how can I understand and predict Structure-Kinetics relationships?” We will first review the role of binding kinetics in drug action and then focus on the particular case of protein-ligand non-covalent complexes, reviewing what is known so far about the structural determinants of binding kinetics. This course will help you with a better understanding and increased awareness of current state of the chemistry and pharmacology of binding kinetics.

Publications, Reports, & Whitepapers
Biomarkers: Neurobiomarkers and Neurodiagnostics
Biomarkers: Discovery and Development for a Diagnostic Approach to Neurodegenerative Disorders, published by Insight Pharma Reports has a focus in biomarkers for neurodegenerative diseases and diagnostic applications in development.
MicroRNA: An Insight to miRNA-based microarrays, diagnostics and therapeutics
This report analyzes recent trends in medicinal chemistry and evaluates their significance for advancing R&D productivity. We consider technological modalities and market dynamics, with an emphasis on outsourcing and user views on the implications of current practices.